• How docetaxel entrapment, vesicle size, zeta potential and stability change with liposome composition–A formulation screening study 

      Holsæter, Ann Mari; Wizgird, Kristina; Karlsen, Iselin; Hemmingsen, Jeanette Frimand; Brandl, Martin; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-21)
      Limitations of the anticancer drug product Taxotere® have encouraged researchers to entrap the active ingredient docetaxel (DTX) into nanocarriers such as liposomes. However, until now no DTX-liposome formulation has reached the clinic. Hence, in the present study, different Soy-PC based DTX-liposome formulations were screened in an attempt to identify lipid-compositions with promising DTX-entrapment ...